A new search engine for researchers: having trouble looking for that antibody?

Added by Branwen Hide on 14 April 2009 16:30

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This is a sort of follow on to a number of my past blog posts on open science, data sharing and web 2.0 as I thought it was a good example of how all these areas feed into each other and can benefit researchers.

It also relates to a personal frustration, of looking for a specific antibody/protein/receptor only to find out I have been using the wrong name to find it.

Antibodies play an important role in modern pharmaceutical research but often it is difficult to find out useful information about them as the gene and proteins names do not have a standard nomenclature. Though the CD nomenclature was developed to classify the many monoclonal antibodies generated by different laboratories around the world, it is not always used to in the literature.

The approximate 5000, 000- 1,000,000 human proteins have an average five synonyms and often a number of different spelling variants. Recently a Transinsight, RESprotect and TU Dresden have received two years of funding to develop a search engine specifically designed to find antibodies mentioned in scientific and non-scientific texts.

The hope is that this will enable researchers to access more information about a specific antibody and ultimately lead to better and quicker drug development. The second phase will see the development of a platform to elucidate interaction networks that will integrate all the textual information about a know compound to better understand the potential activity of a resulting drug.

 

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